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Endocannabinoid System

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Abnormalities in neuroendocrine stress response in psychosis: the role of endocannabinoids.

Agonistic Properties of Cannabidiol at 5-HT1a Receptors.

Anandamide and 2-arachidonoylglycerol: Pharmacological Properties, Functional Features, and Emerging Specificities of the Two Major Endocannabinoids.

Antiangiogenic Activity of the Endocannabinoid Anandamide: Correlation to its Tumor Suppressor Efficacy.

An Update on Non-CB1, Non-CB2 Cannabinoid Related G-Protein-Coupled Receptors.

Biphasic Effects of Cannabinoids on Acetylcholine Release in the Hippocampus: Site and Mechanism of Action.

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro.

​Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors.

Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.

Cannabinoid pharmacology: the first 66 years. 

Cannabinoid receptors and endocannabinoids: Evidence for new players. 

Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in Brain. 

Cannabinoid system and cyclooxygenases inhibitors.

Cannabinoid receptors and their ligands.

Cannabis, a complex plant: different compounds and different effects on individuals.

Cannabis and endocannabinoid modulators: Therapeutic promises and challenges.

Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System.

Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes.

Clinical endocannabinoid deficiency (CECD) revisited: can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

Dose-Related Differences in the Regional Pattern of Cannabinoid Receptor Adaptation and in Vivo Tolerance Development to Δ9-Tetrahydrocannabinol. 

Endocannabinoid Signaling Regulates Sleep Stability.

​Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown.

Endocannabinoid CB1 receptor-mediated rises in Ca2+ and depolarization-induced suppression of inhibition within the laterodorsal tegmental nucleus.

​Endocannabinoids and the haematological system.

Endocannabinoid signalling and the deteriorating brain.

Endocannabinoid System in First Trimester Placenta: Low FAAH and High CB1 Expression Characterize Spontaneous Miscarriage.

Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. 

Enhanced discriminative stimulus effects of Δ9-THC in the presence of cannabidiol and 8-OH-DPAT in rhesus monkeys. 

​Estrogen Receptor Beta and 2-arachidonoylglycerol Mediate the Suppressive Effects of Estradiol on Frequency of Postsynaptic Currents in Gonadotropin-Releasing Hormone Neurons of Metestrous Mice: An Acute Slice Electrophysiological Study.

Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity.

Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist.

Fatty Acid-binding Proteins (FABPs) Are Intracellular Carriers for Δ9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD).

Hardwiring the Brain: Endocannabinoids Shape Neuronal Connectivity.

Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes.

Mitochondria: a possible nexus for the regulation of energy homeostasis by the endocannabinoid system?

Modulating the endocannabinoid system in human health and disease - successes and failures.

Neuropharmacology of the Endocannabinoid Signaling System-Molecular Mechanisms, Biological Actions and Synaptic Plasticity.

Pharmacokinetics and Metabolism of the Plant Cannabinoids, Δ9-Tetrahydrocannibinol, Cannabidiol and Cannabinol. 

Recent advances in cannabinoid receptor agonists and antagonists.

Relationships between eicosanoids and cannabinoids.

Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes.

Role of the Endocannabinoid System in the Neuroendocrine Responses to Inflammation

Role and Function of Endocannabinoid System in Major Depressive Disease.

Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities.

The diverse CB1and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.

The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance.

The endocannabinoid-CB receptor system: Importance for development and in pediatric disease.

The endocannabinoid system and migraine.

The Endocannabinoid System: A New Target for the Regulation of Energy Balance and Metabolism

The Endocannabinoid System as an Emerging Target of Pharmacotherapy.

The Endocannabinoid System, Cannabinoids, and Pain.

The endocannabinoid system drives neural progenitor proliferation.

The endocannabinoid system in normal and pathological brain ageing.

The endogenous cannabinoid system and its role in nociceptive behavior.

The orphan receptor GPR55 is a novel cannabinoid receptor.

The role of endogenous cannabinoids in the hypothalamo-pituitary-adrenal axis regulation: in vivo and in vitro studies in CB1 receptor knockout mice.

The therapeutic potential of novel cannabinoid receptors.

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